The Wuzi Yanzong formula consists of five types of seeds: Cuscutae semen (Cuscuta chinensis), Lycii fructus (Lycium barbarum), Rubi fructus (Rubus chingii), Schizandrae fructus (Schizandra chinensis), and Plantaginis semen (Plantago asiatica) [16 (link)]. The herbal seeds were obtained from Ominherb (Deagu, Korea). Microcrystalline cellulose (MCC, Heweten® 102, JRS Pharma, Rosenberg, Germany), croscarmellose sodium (CCS, Ac-Di-Sol®, FMC biopolymer, Philadelphia, PA, USA), crospovidone (Cros, Kollidone® CL, BASF, Ludwigshafen, Germany), silicon dioxide (SiO2, Aerosil®-200, Evonic Degussa, Essen, Germany), and magnesium stearate (Mg St, FACI, Jurong Island, Singapore) were purchased from Whawon Pharm (Seoul, Korea). All of the other reagents were of analytical or of high-performance liquid chromatograpy (HPLC) grade.
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