Standardized Procedures for Mouse Phenotyping

Standardized, consortium-wide protocols are available at the IMPC portal (www.mousphenotype.org/impress). These procedures define the minimum standards, metadata and protocols for all publically available data. All mouse experiments were conducted in accordance with the governmental and funding regulations of the different member centres. Details of individual centre-specific methods are posted with the IMPReSS procedures. Additional details are provided below.

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Dickinson M.E., Flenniken A.M., Ji X., Teboul L., Wong M.D., White J.K., Meehan T.F., Weninger W.J., Westerberg H., Adissu H., Baker C.N., Bower L., Brown J.M., Caddle L.B., Chiani F., Clary D., Cleak J., Daly M.J., Denegre J.M., Doe B., Dolan M.E., Edie S.M., Fuchs H., Gailus-Durner V., Galli A., Gambadoro A., Gallegos J., Guo S., Horner N.R., Hsu C.W., Johnson S.J., Kalaga S., Keith L.C., Lanoue L., Lawson T.N., Lek M., Mark M., Marschall S., Mason J., McElwee M.L., Newbigging S., Nutter L.M., Peterson K.A., Ramirez-Solis R., Rowland D.J., Ryder E., Samocha K.E., Seavitt J.R., Selloum M., Szoke-Kovacs Z., Tamura M., Trainor A.G., Tudose I., Wakana S., Warren J., Wendling O., West D.B., Wong L., Yoshiki A., MacArthur D.G., Tocchini-Valentini G.P., Gao X., Flicek P., Bradley A., Skarnes W.C., Justice M.J., Parkinson H.E., Moore M., Wells S., Braun R.E., Svenson K.L., de Angelis M.H., Herault Y., Mohun T., Mallon A.M., Henkelman R.M., Brown S.D., Adams D.J., Lloyd K.C., McKerlie C., Beaudet A.L., Bucan M, & Murray S.A. (2016). High-throughput discovery of novel developmental phenotypes. Nature, 537(7621), 508-514.

Publication 2016

Mouse Posted procedures

Corresponding Organization :

Other organizations : Radiation Biophysics Laboratory, Toronto Centre for Phenogenomics, University of Pennsylvania, Mary Lyon Centre at MRC Harwell, Medical Research Council, Wellcome Sanger Institute, European Bioinformatics Institute, Wellcome Trust, Medical University of Vienna, Jackson Laboratory, University of California, Davis, Institute of Cell Biology and Neurobiology, National Research Council, Massachusetts General Hospital, Helmholtz Zentrum München, Baylor College of Medicine, Model Animal Research Center, Nanjing University, Inserm, Centre National de la Recherche Scientifique, Institut Clinique de la Souris, Institut de génétique et de biologie moléculaire et cellulaire, Université de Strasbourg, RIKEN BioResource Research Center, Hospital for Sick Children, The Francis Crick Institute

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Variable analysis

independent variables

Not explicitly mentioned

dependent variables

Not explicitly mentioned

control variables

Standardized, consortium-wide protocols are available at the IMPC portal (www.mousphenotype.org/impress). These procedures define the minimum standards, metadata and protocols for all publically available data. All mouse experiments were conducted in accordance with the governmental and funding regulations of the different member centres. Details of individual centre-specific methods are posted with the IMPReSS procedures.

controls

No specific positive or negative controls were mentioned.

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