A team of trained professional research assistants completed the viscoelastic assays. Citrated blood samples were analyzed using the TEG 5000 Thrombelastography Hemostasis Analyzer (Haemonetics, Niles, IL, USA) as previously described [22 (link)]. The rapid TEG (activated by tissue factor and kaolin) was employed and the following indices were obtained from the tracings of the TEG: activated clotting time [ACT (s)], angle (°), maximum amplitude [MA (mm)], and lysis 30 min after MA [LY30 (%)]. Definitions for fibrinolysis phenotypes by rTEG were shutdown (≤ 0.9%), physiologic (> 0.9–≤ 2.9%), and hyperfibrinolysis (≥ 3%) as previously described [15 (link)].
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Viscoelastic Assay of Citrated Blood
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Other organizations : University of Colorado Denver
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Variable analysis
independent variables
- Activated by tissue factor and kaolin
- Activated clotting time [ACT (s)]
- Angle (°)
- Maximum amplitude [MA (mm)]
- Lysis 30 min after MA [LY30 (%)]
- Fibrinolysis phenotypes: shutdown (≤ 0.9%), physiologic (> 0.9–≤ 2.9%), and hyperfibrinolysis (≥ 3%)
- Citrated blood samples
- No positive or negative controls were explicitly mentioned.
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