Profiling Human Medulloblastomas via Microarray

Human primary medulloblastomas were profiled on Affymetrix Genechip Human Exon 1.0ST arrays at The Centre for Applied Genomics in Toronto, Canada (www.tcag.ca). Expression analysis was performed using Affymetrix Expression Console (Version 1.1) as previously described [26 (link)]. Additional, publically available medulloblastoma expression data sets were obtained from NCBI Gene Expression Omnibus and used to validate our findings [9 (link),27 (link)]. Subgrouping of tumors was performed using an 84-gene expression classifier [28 (link)].

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Jenkins N.C., Kalra R.R., Dubuc A., Sivakumar W., Pedone C.A., Wu X., Taylor M.D, & Fults D.W. (2014). Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma. Acta Neuropathologica Communications, 2, 85.

Publication 2014

Genechip Human Exon 1.0ST arrays Expression Console (Version 1.1)

Exon Gene expression Genechip Human Medulloblastoma Tumors

Corresponding Organization :

Other organizations : University of Utah, Brigham and Women's Hospital, University of Toronto

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Variable analysis

independent variables

Medulloblastoma tumor samples

dependent variables

Gene expression profiles

control variables

Not explicitly mentioned

controls

Positive controls: Not mentioned
Negative controls: Not mentioned

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