Spectral CT Imaging of Thyroid Lesions

This study was approved by the Institutional Review Board, and the requirement for written informed consent from patients was waived. A population database consisting of 92 patients with incidental thyroid nodules who underwent unenhanced and contrast-enhanced gemstone spectral CT scans between August 2016 and December 2017 was queried to identify patients suffering from thyroid papillary carcinoma or nodular goiter confirmed by postoperative histopathology. Thyroid adenomas and medullary carcinoma were excluded due to obviously cystic change and collarbone artifacts on lesions. A total of 81 patients were ultimately eligible for inclusion. The following 26 patients were excluded: (1) disease recurrence, (2) nodular goiter with complete cystic change, (3) previous treatment, (4) with thyroiditis, (5) lesions <1.0 cm [20 (link)], and (6) poor image quality. Finally, 55 GS patients were included in this study (Figure 1).

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Yao C., Chen X., Yang Z., Huang R., Zhang S., Liao Y., Chen X, & Dai Z. (2023). Gemstone Spectral CT Virtual Noncontrast Images and Iodine Maps for the Characterization of Thyroid Lesions and Distinguishing Thyroid Papillary Carcinoma from Nodular Goiter. International Journal of Endocrinology, 2023, 8220034.

Publication 2023

Collarbone Ct scans Cystic Institutional review board Medullary carcinoma Nodular goiter Patients Recurrence Thyroid adenomas Thyroid nodules Thyroid papillary carcinoma Thyroiditis

Corresponding Organization : Sun Yat-sen University

Other organizations : Meizhou City People's Hospital, Shantou University, First Affiliated Hospital of Shantou University Medical College

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Variable analysis

independent variables

Unenhanced and contrast-enhanced gemstone spectral CT scans

dependent variables

Thyroid papillary carcinoma or nodular goiter confirmed by postoperative histopathology

control variables

Thyroid adenomas and medullary carcinoma were excluded due to obviously cystic change and collarbone artifacts on lesions
Patients with disease recurrence, nodular goiter with complete cystic change, previous treatment, thyroiditis, and lesions <1.0 cm were excluded

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