Fluoxetine hydrochloride and Citalopram hydrobromide (Sigma-Aldrich) were dissolved in 0.9% sterile saline. Both drugs were administered in a dose of 10 mg/kg/ml based on previous studies14 (link),30 (link),31 (link) and injected i.p. Chronic treatment consisted of daily administration during 21 days after fear conditioning or extinction protocols depending on the experiment performed.
Muscimol (1 µg/µl; Sigma Aldrich) was dissolved in phosphate-buffered saline (PBS) and bilaterally infused (0.5 µl/side) into dorsal hippocampus 15 min before memory retrieval.
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