Muscimol (1 µg/µl; Sigma Aldrich) was dissolved in phosphate-buffered saline (PBS) and bilaterally infused (0.5 µl/side) into dorsal hippocampus 15 min before memory retrieval.
Chronic SSRI and Hippocampal Muscimol Infusion
Muscimol (1 µg/µl; Sigma Aldrich) was dissolved in phosphate-buffered saline (PBS) and bilaterally infused (0.5 µl/side) into dorsal hippocampus 15 min before memory retrieval.
Corresponding Organization :
Other organizations : Universidade Federal do Rio Grande do Sul, Universidade Federal de Santa Catarina
Variable analysis
- Fluoxetine hydrochloride (Sigma-Aldrich)
- Citalopram hydrobromide (Sigma-Aldrich)
- Muscimol (Sigma Aldrich)
- Fear conditioning or extinction
- 0.9% sterile saline (for Fluoxetine hydrochloride and Citalopram hydrobromide)
- Phosphate-buffered saline (PBS) (for Muscimol)
- Previous studies (references 14, 30, 31) used the same doses of Fluoxetine hydrochloride and Citalopram hydrobromide
- No negative controls are explicitly mentioned
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