Oseltamivir Phosphate was obtained from Sigma-Aldrich. Oseltamivir was administered orally twice a day at 0.1 mg/g one day prior to infection [20 (link)]. Sialidase was purchased from Roche. Mice were treated with 0.012 U Sialidase in phosphate buffered saline (PBS) i.p. The treatment was performed twice a day, starting one day prior to infection. The treatment was adjusted from the published protocol [21 (link)].
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