Microcystin-LR and TQ-induced Inflammation

Microcystin -LR; (CAS No 101043-37-2, molecular weight 995.189 g/mol; purity ≥ 98.5%) and TQ-(2-isopropyl-5-methylbenzo-1,4-quinone, CAS № 490-91-5, molecular weight 2164.204 g/mol; purity ≥ 98.5%) were purchased from Sigma–Aldrich (Saint Louis, MO, USA). Biochemical kits used were procured from the Laboratory Bio Diagnostics Company (Cairo, Egypt), except for lactate dehydrogenase (LDH) kits obtained from (Randox Laboratories Ltd., UK). Interleukin-1β (IL-1β) and interleukin-6 (IL-6) were purchased from Glory Science Co. Ltd. (Del Rio, TX, USA), and tumor necrosis factor-α (TNF-α) was obtained from Bio Source International Inc. (Camarillo, CA, USA) for inflammatory reaction assessment.