In Vivo 31P MRS of Healthy Brain

Ten in vivo ³¹P MRS datasets, which were acquired from five healthy participants (mean age 26.8 ± standard deviation 7.7 years) at 3 Tesla and five healthy participants (age 33.5 ± 10.3 years) at 7 Tesla [11 (link)], were analyzed in this study. The data acquisition procedures have been described previously [11 (link)]. Briefly, MRS measurements were performed on Siemens Skyra 3 Tesla and Magnetom 7 Tesla scanners (Siemens Healthcare, Erlangen, Germany) using home-built coil assemblies composed of a circular ³¹P coil with a 7.0 cm diameter and a quadrature half-volume ¹H coil. In vivo ³¹P MRS spectra were acquired without ¹H decoupling. Acquisition parameters at 3 Tesla were as follows: TR = 2 s; spectral width = 5 kHz; number of acquisitions = 128; number of data points = 1024. Identical parameters were used for 7 Tesla data acquisition, except that TR = 3 s.