Prednisolone Dose Modification Audit

Prescription modification for prednisolone doses was investigated, and 135 prescriptions with dose modification were defined as positive cases. For positive cases, the dose in the pre-revision order (first edition) was investigated. Positive cases included dose-related changes (i.e., increase or decrease in the daily dose, addition and deletion of prednisolone tablets, or changes in the strength of prednisolone tablets). Changes in prescribing days, comments, and other concomitant medications were not considered positive cases. Eighty-two thousand four hundred eighteen prescriptions without dose modification were considered negative case. There was significant imbalance in the outcome, with a positive rate of 0.16%
The following features have been adapted to build a predictive model in the pharmacy prescription audit setting: the cluster of clinical departments, current daily dose (pre-revision dose in positive case), current prescription days (pre-revision days in positive case), daily dose of the previous prescription, and prescription days of the previous prescription.