Seventy-nine right-handed subjects were enrolled in this study, including 39 bvFTD patients, from July 1, 2014, to October 31, 2021, in the Department of Neurology of Xuanwu Hospital. All patients were diagnosed with probable bvFTD according to the consensus criteria published in 2011 [18 (link)]. Age- and sex-matched healthy controls who had no complaints of cognitive decline, depression, or anxiety and performed within the normal range on neuropsychological tests (Mini-Mental State Examination [MMSE] score ≥ 24 and Clinical Dementia Rating Scale [CDR] score = 0) were enrolled from communities.
Exclusion criteria for all participants were as follows: (1) any serious neuropsychiatric disorder that could affect cognitive function, such as substance abuse, alcoholism, schizophrenia, tumours, or cerebrovascular disease; (2) standard contraindications for MRI examinations; and (3) absence of a reliable informant.
Exclusion criteria for all participants were as follows: (1) any serious neuropsychiatric disorder that could affect cognitive function, such as substance abuse, alcoholism, schizophrenia, tumours, or cerebrovascular disease; (2) standard contraindications for MRI examinations; and (3) absence of a reliable informant.
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