Because ensitrelvir has an inhibitory effect on CYP3A, patients must refrain from consuming any foods and beverages containing grapefruit or Seville oranges and also avoid consuming products containing St. John wort during the study intervention period. Details of prohibited concomitant drugs are provided in the Supplemental Appendix 1, http://links.lww.com/MD/I515.
Free full text: Click here