5-bromo-2′-deoxyuridine (BrdU; cat. no. B5002, Sigma-Aldrich, St. Louis, MO, United States) and 5-iodo-2′-deoxyuridine (IdU; cat. no. I7125, Sigma-Aldrich) were dissolved at a concentration of 15 mg/mL in sterile 0.9% NaCl solution. To assess cell survival, all rats were treated with BrdU at a dose of 50 mg/kg (i.p.) for five consecutive days during the third week of experimentation (Rivera et al., 2015 (link)). To assess cell proliferation, IdU were administered at a dose of 57.65 mg/kg (i.p.) for five consecutive days after the fifth week of experimentation (Figure 1 ).
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