Baseline information at ICU admission included: demographic data, modified Charlson [16 (link)], Simplified Acute Physiology Score II (SAPS II) [17 (link)], SOFA score, underlying thyroid disease, triggering factors, clinical signs, and laboratory findings. Follow-up parameters recorded were the use of vasopressors, inotropic drugs, invasive mechanical ventilation, and renal replacement therapy. In addition, the composite diagnosis score of myxedema coma proposed by Popovenic et al. [18 (link)] which combines the presence or absence of alterations of thermoregulatory, central nervous systems, cardiovascular, gastrointestinal, and metabolic systems, and the presence or absence of a precipitating event, was applied in our cohort. Specific thyroid management (thyroid hormone replacement therapy) and corticosteroid use in ICU were also reported. Finally, survival at ICU discharge and 6-month survival status after ICU admission (through medical charts or contact by phone) was noted.
Bourcier S., Coutrot M., Ferré A., Van Grunderbeeck N., Charpentier J., Hraiech S., Azoulay E., Nseir S., Aissaoui N., Messika J., Fillatre P., Persichini R., Carreira S., Lautrette A., Delmas C., Terzi N., Mégarbane B., Lascarrou J.B., Razazi K., Repessé X., Pichereau C., Contou D., Frérou A., Barbier F., Ehrmann S., de Montmollin E., Sztrymf B., Morawiec E., Bigé N., Reuter D., Schnell D., Ellrodt O., Dellamonica J., Combes A, & Schmidt M. (2023). Critically ill severe hypothyroidism: a retrospective multicenter cohort study. Annals of Intensive Care, 13, 15.
Publication 2023
Cardiovascular Central nervous systems Coma CorticosteroidDiagnosis Discharge Drugs Hormone replacement therapyMechanical ventilation MyxedemaRenal replacement therapy Thermoregulatory Thyroid Thyroid disease Triggering factors Vasopressors
Corresponding Organization :
Other organizations :
Pitié-Salpêtrière Hospital, Sorbonne Université, Assistance Publique – Hôpitaux de Paris, Centre Hospitalier de Versailles, Centre Hospitalier de Lens, Groupe Hospitalier Cochin - Port-Royal, Hôtel-Dieu, Broca - La Collégiale, Hôpital Cochin, Hôpital Nord, Assistance Publique Hôpitaux de Marseille, Hôpital Saint-Louis, Centre Hospitalier Universitaire de Lille, Hôpital Européen Georges-Pompidou, Université Paris Cité, Hôpital Louis-Mourier, Centre Hospitalier de Saint-Brieuc, Centre Hospitalier Universitaire de La Réunion, Hôpital Saint- Camille, Centre Hospitalier Universitaire de Clermont-Ferrand, Hôpital Rangueil, Centre Hospitalier Universitaire de Grenoble, Hôpital Lariboisière, Centre Hospitalier Universitaire de Nantes, Centre Hospitalier Universitaire Henri-Mondor, Hôpital Ambroise-Paré, Centre Hospitalier Intercommunal de Poissy, Centre Hospitalier Victor Dupouy, Hôpital Pontchaillou, Centre Hospitalier Universitaire de Rennes, Centre hospitalier régional d'Orléans, Clinical Investigation Center Plurithematic Tours, French Clinical Research Infrastructure Network, Centre Hospitalier Universitaire de Tours, Inserm, Centre Hospitalier Saint-Denis, Hôpital Antoine-Béclère, Hôpital Saint-Antoine, Centre Hospitalier Sud Francilien, Centre Hospitalier d'Angoulême, Melun Hospital, Centre Hospitalier Universitaire de Nice, Université Côte d'Azur, Fondation pour l’innovation en Cadiométabolisme et Nutrition
Simplified Acute Physiology Score II (SAPS II) [17]
SOFA score
Underlying thyroid disease
Triggering factors
Clinical signs
Laboratory findings
Use of vasopressors
Use of inotropic drugs
Use of invasive mechanical ventilation
Use of renal replacement therapy
Composite diagnosis score of myxedema coma proposed by Popovenic et al. [18]
Specific thyroid management (thyroid hormone replacement therapy)
Corticosteroid use in ICU
dependent variables
Survival at ICU discharge
6-month survival status after ICU admission
control variables
Demographic data
Annotations
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