Standard Tuberculosis Treatment Regimen

The patients were treated using the WHO standard 6-month regimen that included 2 months of isoniazid/rifampicin/pyrazinamide/ethambutol and 4 months of isoniazid/rifampicin (2HRZE/4HR). The directly observed therapy (DOT) strategy was followed in the intensive phase of treatment, while community volunteers were involved in monitoring the patients in the continuous phase. During the initial and follow-up visits, the patients were told to report any symptoms they developed that may indicate the relapse of the disease to their TB unit. Consequently, when the patients returned to their TB unit with any symptoms associated with TB, a chest X-ray was performed, and a sputum acid-fast bacilli smear test was conducted when TB relapse was suspected [25 (link)].

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Anaam M.S, & Alrasheedy A.A. (2023). Recurrence Rate of Pulmonary Tuberculosis in Patients Treated with the Standard 6-Month Regimen: Findings and Implications from a Prospective Observational Multicenter Study. Tropical Medicine and Infectious Disease, 8(2), 110.

Publication 2023

Acid Bacilli Chest x ray Directly observed therapy Ethambutol Isoniazid Patients Pyrazinamide Regimen Relapse Rifampicin Sputum Volunteers

Corresponding Organization : Qassim University

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Variable analysis

independent variables

WHO standard 6-month regimen that included 2 months of isoniazid/rifampicin/pyrazinamide/ethambutol and 4 months of isoniazid/rifampicin (2HRZE/4HR)
Directly observed therapy (DOT) strategy in the intensive phase of treatment
Community volunteers involved in monitoring the patients in the continuous phase

dependent variables

Relapse of the disease
Chest X-ray performed when TB relapse was suspected
Sputum acid-fast bacilli smear test conducted when TB relapse was suspected

control variables

Independent variables not explicitly mentioned.
Dependent variables not explicitly mentioned.
Positive and negative controls not specified by authors.

Annotations

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