TLR Agonists for Immunomodulation

TLR3 agonist (Poly(I:C) HMW, vac-pic) was purchased from InvivoGen (San Diego, CA). TLR9 agonist (ODN 1826) was obtained from Integrated DNA Technologies (San Diego, CA). Both agonists were dissolved in endotoxin-free physiological water from InvivoGen (San Diego, CA). Doses chosen for administration to animals were as previously reported.12 (link)

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Jeon D., Hill E., Moseman J.E, & McNeel D.G. (2024). Combining toll-like receptor agonists with immune checkpoint blockade affects antitumor vaccine efficacy. Journal for Immunotherapy of Cancer, 12(5), e008799.

Publication 2024

ODN 1826

Corresponding Organization : University of Wisconsin–Madison

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Variable analysis

independent variables

TLR3 agonist (Poly(I:C) HMW, vac-pic)
TLR9 agonist (ODN 1826)

dependent variables

Not explicitly mentioned

control variables

Doses chosen for administration to animals were as previously reported.12

controls

Positive control: Not specified
Negative control: Not specified

Annotations

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