ECV imaging was performed between Sept 2009 and May 2011, 952 patients referred for CMR assessment of known or suspected heart disease prospectively underwent ECV imaging. Hematocrit was measured from a venous blood sample drawn just prior to the CMR study. This study was approved by the local Institutional Review Boards of the National Heart, Lung, and Blood Institute and Suburban Hospital, and all subjects gave written informed consent to participate. A total of 1680 ECV maps were generated by automated off-line processing as described above (728 studies imaged matching short and long axis views both pre- and post-contrast, and the 224 remaining studies only acquired a single slice). Scoring of ECV map quality was performed on 600 maps (338 subjects) acquired consecutively, and statistics for automatic blood measurements were made based on the complete set. Additionally, cine MRI of cardiac function and phase sensitive inversion recovery (PSIR) late Gadolinium enhancement imaging [22 (link)] was performed on all subjects.
Free full text: Click here
