Generation and Maintenance of NOD Mice

NOD/ShiLtJ (NOD) mice were originally obtained from The Jackson Laboratory. All mice were bred, maintained, and used in experiments in our pathogen-free animal facility in accordance with the guidelines of the Division of Comparative Medicine at Washington University School of Medicine (Association for Assessment and Accreditation of Laboratory Animal Care accreditation no. A3381-01). NOD.IAPP^−/− mice were previously bred in the Haskins mouse colony by backcrossing C57BL6.IAPP^−/− mice (20 (link)) onto the NOD background (21 (link)).

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Wenzlau J.M., Peterson O.J., Vomund A.N., DiLisio J.E., Hohenstein A., Haskins K, & Wan X. (2024). Mapping of a hybrid insulin peptide in the inflamed islet β-cells from NOD mice. Frontiers in Immunology, 15, 1348131.

Publication 2024

NOD/ShiLtJ (NOD) mice

Corresponding Organization :

Other organizations : University of Colorado Denver

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Variable analysis

independent variables

Genotype (NOD mice vs. NOD.IAPP^-/- mice)

dependent variables

Not explicitly mentioned

control variables

Pathogen-free animal facility
Animal care guidelines of the Division of Comparative Medicine at Washington University School of Medicine

controls

Positive control: Not specified
Negative control: Not specified

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