Plant-Derived Peptides with Bioactivities

FASTA sequences from plant-derived peptides and proteins with immunomodulatory, anti-inflammatory, and anticancer bioactivities, i.e., AMPs, OSIPs, and STPIs, were obtained from the entries collected after a protein source search (filtered by plant organism) with the keywords antimicrobial peptide, oxidative stress induced peptide, and serine-type protease inhibitor in the National Center for Biotechnology Information database (NCBI, https://www.ncbi.nlm.nih.gov/protein, accessed on 1 November 2022). For AMPs, the keywords cycloviolacin O₂ from viola odorata, gamma-thionin from capsicum chinense, kalata B1 from oldenlandia affinis, NaD1 from nicotiana alata, pyrularia from pyrularia pubera, and Varv from viola arvensis were also included because, despite the fact that they are not returned under the keyword antimicrobial peptide, they are classified as AMPs with recognized antimicrobial, immune-regulatory, and anticancer activities [9 (link)]. FASTA protein sequences for AMPs, OSIPs, and STPIs can be found in Supplementary Datafiles S1, S2, and S3, respectively.