Cervical Lymph Node Mapping Protocol
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Corresponding Organization : Osaka Medical and Pharmaceutical University
Protocol cited in 2 other protocols
Variable analysis
- Injection of 2.0 ml of fluid containing 110 MBq 99m-Technetium (99mTc)-labeled tin colloids into the patient's cervix
- Injection of 5 ml of indigocarmine (IDC) (2 mg/mL) and/or indocyanine green (ICG) (50 μg/mL) into the cervix at the start of surgery
- Injection of the same quantity of IDC and/or ICG into the uterine fundus upon reaching the intraabdominal cavity
- Identification of hot spots (indicating SLNs) using lymphoscintigraphy within 6 hours of injection
- Detection of radioactive lymph nodes using a gamma-probe
- Detection of IDC-stained lymph nodes by direct inspection
- Detection of ICG fluorescence-positive lymph nodes using a color fluorescence camera
- Confirmation that no radioactive tissue remained after SLN biopsy by direct observation and with a color fluorescence camera or a gamma-probe
- The cervical injection was approximately 5 mm in all cases, as described previously
- The combination of 99mTc and IDC was used in the early phase and a combination of 3 tracers was used in the late phase
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