Retrospective Analysis of ICU Patients with Diabetes

A retrospective analysis was conducted on 998 severely ill patients with diabetes and without diabetes who were admitted to the ICU of the First Affiliated Hospital of Jinan University from January 1, 2019 to December 31, 2020, which consisted of 250 diabetic patients (DM group) and 748 non-diabetic patients (ND group). All patients were older than 18 years and had been treated in the ICU for at least 1 day. Exclusion criteria were: (1) incomplete death data; (2) in the ICU for less than 24 h; (3) less than 6 blood glucose measurements on the first day after admission; (4) family members gave up treatment; (5) hospital stay exceeded 120 days. The diagnostic criteria for diabetes were based on the 1999 World Health Organization criteria and were determined using the information provided when entering the ICU. Due to the critical and fluctuating conditions of patients with severe diseases, oral glucose tolerance test and HbA1c test were not available; thus, it was not possible to evaluate and diagnose underlying diabetes, and no differentiation was made between type 1 diabetes and type 2 diabetes. The patient's information was extracted from the ICU information system and the hospital's electronic medical record system. The collected information included demographic information, patient diagnosis and comorbidities, past medical history, disease severity score (APACHE II score), ICU hospital stay, blood glucose, hemodialysis days, ventilator-assisted time, other biochemical indicators, and patient outcomes. The ICU information data system does not contain detailed information on the dosage and duration of insulin used by patients; thus, this information was not included in our study. Nutritional support therapy was guided by a standardized program that emphasizes early enteral feeding. During ICU hospitalization, around 10–15% of patients received complete enteral nutrition, and the nutritional support status of these patients was not included in the ICU information data system; thus, it could not be analyzed in this study.

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Yu G., Ma H., Lv W., Zhou P, & Liu C. (2023). Association of the time in targeted blood glucose range of 3.9–10 mmol/L with the mortality of critically ill patients with or without diabetes. Heliyon, 9(3), e13662.

Publication 2023

Blood glucose Diabetes Diagnosis Enteral nutrition Family members Hemodialysis Hospitalization Insulin Nutritional therapy Oral glucose tolerance test Patients Type 1 diabetes Type 2 diabetes

Corresponding Organization :

Other organizations : Jinan University, First Affiliated Hospital of Jinan University

Top 5 similar protocols

Variable analysis

independent variables

Presence of diabetes (DM group vs ND group)

dependent variables

ICU hospital stay
Blood glucose
Hemodialysis days
Ventilator-assisted time
Patient outcomes

control variables

Patients older than 18 years
Patients treated in the ICU for at least 1 day
Exclusion criteria: (1) incomplete death data; (2) in the ICU for less than 24 h; (3) less than 6 blood glucose measurements on the first day after admission; (4) family members gave up treatment; (5) hospital stay exceeded 120 days

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