Handheld Gamma-Camera SLN Assessment

Immediately following lymphoscintigraphy, SLN assessment was preoperatively performed using the handheld gamma-camera by a single observer while blinded for lymphoscintigraphy (n = 36; 68%). Identified hotspots using the handheld gamma-camera were recorded and designated as either SLN or HEN on the basis of their location and relative radioactive intensity. Subsequently, the results of lymphoscintigraphy including SPECT/CT, as reviewed by a nuclear physician, were revealed to the blinded observer. Any discrepancies between lymphoscintigraphy and handheld gamma-camera outcomes were registered. If SLNs were missed by blinded assessment using the handheld gamma-camera, an additional assessment was conducted to determine whether missed SLNs could be identified with either the handheld gamma-camera or gamma-probe with information provided by lymphoscintigraphy. In all patients, lymphoscintigraphy was leading in designating SLNs for biopsy.

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Mahieu R., Tijink B.M., van Es R.J., van Nierop B.J., Beijst C., de Keizer B, & de Bree R. (2023). The potential of the Crystal Cam handheld gamma-camera for preoperative and intraoperative sentinel lymph node localization in early-stage oral cancer. European Archives of Oto-Rhino-Laryngology, 280(12), 5519-5529.

Publication 2023

Biopsy Gamma Gamma camera Lymphoscintigraphy Patients Physician Radioactive Spect ct

Corresponding Organization :

Other organizations : University Medical Center Utrecht, Heidelberg University, University Hospital Heidelberg

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Variable analysis

independent variables

Handheld gamma-camera assessment by a single observer while blinded for lymphoscintigraphy

dependent variables

Identified hotspots using the handheld gamma-camera, designated as either SLN or HEN on the basis of their location and relative radioactive intensity
Discrepancies between lymphoscintigraphy and handheld gamma-camera outcomes
Identification of missed SLNs by blinded assessment using the handheld gamma-camera

control variables

Lymphoscintigraphy, including SPECT/CT, as reviewed by a nuclear physician
Information provided by lymphoscintigraphy for additional assessment to determine whether missed SLNs could be identified

positive controls

Lymphoscintigraphy, including SPECT/CT, as reviewed by a nuclear physician was leading in designating SLNs for biopsy

negative controls

Not explicitly mentioned

Annotations

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