A total of 6, 020 consecutive patients with CRC who were admitted to Shanghai Changzheng Hospital from July 2010 to June 2021 were selected. The study was approved by the ethics committee of Shanghai Changzheng hospital. The clinical data collected included age, gender, tumor metastasis, HBV carrier status, blood type, CEA, CA199, AFP, primary tumor location, primary tumor diameter, tissue type, degree of differentiation, and depth of tumor invasion. Locations of the primary tumor were divided into left colon, right colon, and rectum. Diameter of the primary tumor was divided into ≤3 cm and >3 cm according to the size. Tissue types were divided into adenocarcinoma and other types (carcinoid, signet ring cell carcinoma, mucinous adenocarcinoma, etc.). Degrees of differentiation were divided into undifferentiated-poor differentiation and medium-well differentiation. Depths of invasion were divided into T1-2 group and T3-4 according to the TNM staging standard formulated by AJCC. Each patient selectively underwent X-ray, abdominal B-ultrasound, chest CT, abdomen CT, abdominal MRI, or PET-CT according to the diagnosis and treatment needs.
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