HEK293T cells as well as Caco-2 cells were from Sigma Aldrich (St. Louis, MO, USA). HEK293T cells and ADAM10/ADAM17 double-deficient HEK293 cells [30 (link)] were grown in DMEM (High glucose; Thermo Fisher Scientific) supplemented with 10% fetal calf serum (FCS) and 1% penicillin/streptomycin (Pen/Strep). Caco-2 cells were cultured in RPMI (Thermo Fisher Scientific) with 10% FCS and 1% Pen/Strep.
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