Data acquisition and analyses including calibration curves were carried out using Waters TargetLynx V4.1 software. The homoeostatic model assessment percentage insulin sensitivity (HOMA2%S) was calculated using the iHOMA2 software, using default settings.
22 (link) Other statistical analyses were carried out using STATA 15.1 (STATACorp LLC). The distribution of parameters was assessed using kernel density plots and Q‐Q plots versus idealised normal distributions. A repeated‐measures linear mixed model was used for analysis of glucose, insulin and PYY concentrations as well as the area‐under‐concentration curve (AUC) analysis. GraphPad Prism 9.0.2 (GraphPad Software) was used for the calculation of AUC values using the trapezoid method. For the purposes of analysis, analyte concentrations smaller than the LLOQ were set at zero.
22 (link) Other statistical analyses were carried out using STATA 15.1 (STATACorp LLC). The distribution of parameters was assessed using kernel density plots and Q‐Q plots versus idealised normal distributions. A repeated‐measures linear mixed model was used for analysis of glucose, insulin and PYY concentrations as well as the area‐under‐concentration curve (AUC) analysis. GraphPad Prism 9.0.2 (GraphPad Software) was used for the calculation of AUC values using the trapezoid method. For the purposes of analysis, analyte concentrations smaller than the LLOQ were set at zero.
Free full text: Click here
