Quantitative measurements were performed on a dedicated workstation (Syngo TrueD, Siemens Medical Solutions).
Volume of interest (VOI) was performed using a 40% threshold of SUVmax. The SUVmax, SUVmean and MTV were obtained for each identified lung lesion. TLG defined as MTV multi-plied by the average SUV uptake (SUVmean) within the MTV. We used the liver as a source for the background and noise measurement [13 (link)]. In each patient, a 30 mm-diameter spherical VOI was placed within an area of uniform FDG distribution in the liver, the mean SUV and standard deviation within the VOI were obtained. The signal-to-nose ratio of the tumour, relative to the liver, SNR (T–L) was calculated as: where the Tumour refers to SUVmax in the lung lesion, Liver and SDL is the mean SUV and standard deviation measured in the liver VOI respectively.
Volume of interest (VOI) was performed using a 40% threshold of SUVmax. The SUVmax, SUVmean and MTV were obtained for each identified lung lesion. TLG defined as MTV multi-plied by the average SUV uptake (SUVmean) within the MTV. We used the liver as a source for the background and noise measurement [13 (link)]. In each patient, a 30 mm-diameter spherical VOI was placed within an area of uniform FDG distribution in the liver, the mean SUV and standard deviation within the VOI were obtained. The signal-to-nose ratio of the tumour, relative to the liver, SNR (T–L) was calculated as: where the Tumour refers to SUVmax in the lung lesion, Liver and SDL is the mean SUV and standard deviation measured in the liver VOI respectively.
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