Multimodal Brain Imaging Protocol

Scans were acquired on a GE Discovery MR750 3.0 T system. Pre and post scan sections consisted of (1) a high-resolution anatomical scan (MPRAGE, resolution = 1mm³, 208 slices, FOV = 25.6 cm, TR = 2500 ms, TE = 2.92 ms, FA = 8 deg), (2) resting-state BOLD fMRI scans, and (3) arterial spin labeling (ASL) scans (2D pseudo-continuous ASL (PCASL), single-shot spiral, 100 repetitions, resolution = 3.75 mm × 3.75 mm, slice thickness = 6 mm, matrix size = 64 × 64 × 24, FOV = 24 cm, TE = 3.2 ms, TR = 4300 ms, labeling duration = 1800 ms and post-labeling delay = 1800 ms)^{28 (link)}. Only the anatomical and ASL scans are analyzed here. The resting-state BOLD scans will be analyzed in a separate paper. During all ASL scans, subjects rested with their eyes open and gently focused on a fixation point.