Vaccinia Scarification with Stat3 Inhibition
Corresponding Organization : Center for Biologics Evaluation and Research
Variable analysis
- StatticĀ® (STAT3 inhibitor) was applied prior to vaccinia scarification
- Cyclophosphamide was administered by intraperitoneal route starting with the day prior to vaccinia scarification and every 4 days after vaccinia infection
- Not explicitly mentioned
- Scarification using 10^6 pfu ACAM-2000 was performed as previously described [4 (link)]
- Positive control: Not specified
- Negative control: Not specified
Annotations
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