Cells were seeded into 96-well plates at 1500 cells/well for OVCAR-8, and at 1900 for NCI-H460. After 24 h of incubation, cells were treated with various concentrations of RNase for 72 h. Drug sensitivity was determined by the MTT method essentially following the manufacturer’s instructions (Sigma, Saint Louis, MO, USA) and according to [39 (link)]. All data are presented as the mean ± SE of at least three independent experiments with three replicates for each.
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