Multiresistant and Susceptible Isolate Analysis

For the analysis of MDR and complete susceptibility, a multiresistant isolate is one defined as resistant to at least three of the antimicrobial substances. In contrast, a completely susceptible isolate is one defined as non‐resistant (MIC < ECOFF) to these antimicrobial substances. For indicator E. coli and Salmonella spp., all substances from the harmonised test panel laid out in Commission Implementing Decision (EU) 2020/1729 will be included in the assessment of MDR, which is consistent with the approach taken in the 2019–2020 EUSR on AMR. The substances included will be amikacin/gentamicin (assessed together as aminoglycoside antimicrobial class for 2021 data), ampicillin, azithromycin (macrolide antimicrobial class), cefotaxime/ceftazidime (assessed together as third‐generation cephalosporin), chloramphenicol, ciprofloxacin/nalidixic acid (assessed together as quinolone antimicrobial class), meropenem, sulfamethoxazole, tetracycline/tigecycline (assessed together as glycylcycline antimicrobial class) and trimethoprim. For C. coli and C. jejuni, the substances included will be ciprofloxacin, erythromycin (macrolide antimicrobial class), gentamicin and tetracycline.