In this study, radiomic features extraction was made on volumetric interpolated breath-hold examination (VIBE) T1-weighted SPAIR with controlled respiration used to acquire images after IV CA injection with a liver-specific CA (0.1 mL/kg of Gd-EOB-BPTA, Primovist, Bayer Schering Pharma, Berlin, Germany) as descripted in [26 (link),27 (link)].
The VIBE T1-W sequence was acquired with two different flip angles (10 and 30 degrees). A power injector (Spectris Solaris® EP MR, MEDRAD, Inc., Indianola, IA, USA) was used to administer the CA at an infusion rate of 2 mL/s. VIBE T1-w images were acquired in four different phases: arterial phase (35 s delay), portal venous phase (90 s), late/transitional phase (120 s), and hepatobiliary excretion phase (20 min). MRI protocol details are reported in