A Magnetom Symphony 1.5 T scanner (Siemens, Erlangen, Germany) and a Magnetom Aera (Siemens) 1.5 T scanner equipped with an 8-element body and phased array coils were used to acquire an MRI study that includes sequences before and after intravenous (IV) contrast agent (CA) injection.
In this study, radiomic features extraction was made on volumetric interpolated breath-hold examination (VIBE) T1-weighted SPAIR with controlled respiration used to acquire images after IV CA injection with a liver-specific CA (0.1 mL/kg of Gd-EOB-BPTA, Primovist, Bayer Schering Pharma, Berlin, Germany) as descripted in [26 (link),27 (link)].
The VIBE T1-W sequence was acquired with two different flip angles (10 and 30 degrees). A power injector (Spectris Solaris® EP MR, MEDRAD, Inc., Indianola, IA, USA) was used to administer the CA at an infusion rate of 2 mL/s. VIBE T1-w images were acquired in four different phases: arterial phase (35 s delay), portal venous phase (90 s), late/transitional phase (120 s), and hepatobiliary excretion phase (20 min). MRI protocol details are reported in Table 2.
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