Statistical Analysis of Cognitive Studies

Data analyses. Sample sizes were determined by power analysis using G*Power (v.3.1.9.2) based on previous works published by our lab on CBF regulation cognitive testing [25 (link), 33 (link)]. The experiments were randomized based on the random number generator (https://www.random.org) and were performed and analyzed in a blinded fashion whenever possible. Data and image analyses were done using ImageJ 1.54c (NIH) or Prism 9 for MacOS (GraphPad Software). Data were tested for normal distribution by the D’Agostino–Person test and for outliers by the Grubbs’ test (extreme studentized deviate). Two-group comparisons were analyzed using paired or unpaired two-tailed t-test, as indicated. Multiple comparisons were evaluated by one-way or two-way analysis of variance (ANOVA) and Tukey’s test. Differences were considered statistically significant for probability values less than 0.05. Data are expressed as the mean ± S.E.M.

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Uekawa K., Hattori Y., Ahn S.J., Seo J., Casey N., Anfray A., Zhou P., Luo W., Anrather J., Park L, & Iadecola C. (2023). Border-associated macrophages promote cerebral amyloid angiopathy and cognitive impairment through vascular oxidative stress. Molecular Neurodegeneration, 18, 73.

Publication 2023

Prism 9 for MacOS

Prism

Corresponding Organization :

Other organizations : Cornell University, MIND Research Institute

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Variable analysis

independent variables

Randomization based on random number generator (https://www.random.org)

dependent variables

Measured outcomes

control variables

Experiments performed and analyzed in a blinded fashion whenever possible

controls

No positive or negative controls explicitly mentioned

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