Per standard clinical practice (22 (link),23 ), abdominal MRI examinations had been performed without intravenous contrast material and with an active-passive driver system operated at 60 Hz, utilizing either a two-dimensional gradient recalled echo or two-dimensional spin-echo echo-planar imaging elastography sequence. Four axial slices through the mid liver had been obtained to generate shear wave and elastogram images. Regions of interest had been drawn manually by dedicated Department of Radiology imaging postprocessors for the measurement of liver stiffness (guided by 95% confidence maps), and overall liver stiffness was expressed as the weighted mean of the mean liver stiffness values for each of the four elastograms (22 (link)).
Liver PDFF imaging was performed with IDEAL IQ (GE Healthcare; Waukesha, WI) or mDIXON Quant (Philips Healthcare; Best, The Netherlands). The same postprocessors drew ovoid regions of interest for PDFF measurements that included as much liver parenchyma as possible while excluding large vessels. PDFF measurements were performed on four slices through the mid-liver with overall liver PDFF expressed as a mean of these values.
Liver PDFF imaging was performed with IDEAL IQ (GE Healthcare; Waukesha, WI) or mDIXON Quant (Philips Healthcare; Best, The Netherlands). The same postprocessors drew ovoid regions of interest for PDFF measurements that included as much liver parenchyma as possible while excluding large vessels. PDFF measurements were performed on four slices through the mid-liver with overall liver PDFF expressed as a mean of these values.
