Information collected included age, height, and weight. All patients were required to keep a migraine diary to record visual analogue scale (VAS) scores (scale of 0–10, with 10 being the most intense pain imaginable), migraine attack frequency (number of times), and duration of migraine attack (h). The Headache Impact Test (HIT-6) questionnaire was adopted to assess the impact of migraine on the lives of the patients (Shin et al. 2008 (link)), and the Migraine-Specific Quality of Life Questionnaire (MSQ), a 14-item health-related quality of life questionnaire, was used to measure three dimensions of functional status specific to migraine (using preventive, restrictive, and emotional functional subscales)(Bagley et al. 2012 (link)).
MRI data were acquired with a GE Discovery MR750 3.0 T system with an eight-channel, phased-array head coil (General Electric, Milwaukee, WI, USA). The functional images were obtained with a single-shot gradient-echo echo-planar imaging (GRE-EPI) sequence with the following parameters: repetition time = 2000 ms; echo time = 25 ms; flip angle = 90°, field of view = 240 × 240 mm, data matrix = 64 × 64, slice thickness = 3 mm. During the whole functional scan, all participants were instructed to keep their eyes closed and stay awake during the entire session.
MRI data were acquired with a GE Discovery MR750 3.0 T system with an eight-channel, phased-array head coil (General Electric, Milwaukee, WI, USA). The functional images were obtained with a single-shot gradient-echo echo-planar imaging (GRE-EPI) sequence with the following parameters: repetition time = 2000 ms; echo time = 25 ms; flip angle = 90°, field of view = 240 × 240 mm, data matrix = 64 × 64, slice thickness = 3 mm. During the whole functional scan, all participants were instructed to keep their eyes closed and stay awake during the entire session.
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