Autism Genetic Variants Investigation
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Corresponding Organization :
Other organizations : Hospital for Sick Children, University of Oxford, Wellcome Centre for Human Genetics, University of Pittsburgh, Trinity College Dublin, University of Toronto, University College Dublin, Instituto Gulbenkian de Ciência, National Institute of Health Dr. Ricardo Jorge, Center for Autism and Related Disorders, University of Bologna, Warneford Hospital, Guy's Hospital, Fondazione Stella Maris, Newcastle University, Goethe University Frankfurt, Psychiatry Research Trust, Institut Pasteur, Holland Bloorview Kids Rehabilitation Hospital, SickKids Foundation, Dalhousie University, University of Michigan–Ann Arbor, Vanderbilt University, Carnegie Mellon University, Autism Speaks, University Medical Center Utrecht, Fondation FondaMental, Hôpital Robert-Debré, Assistance Publique – Hôpitaux de Paris, Inserm, University of Washington, Memorial University of Newfoundland, University of Miami, McGill University, University of Gothenburg, Children's Hospital of Philadelphia, McMaster University, University of Illinois at Chicago, Heidelberg University, German Cancer Research Center, Icahn School of Medicine at Mount Sinai, University of Manchester, Hôpital Albert-Chenevier, Nathan Kline Institute for Psychiatric Research, Stanford University, Indiana University – Purdue University Indianapolis, University of Utah, University of California, Los Angeles, Centre for Addiction and Mental Health, Children's Hospital Agia Sophia, Sorbonne Université, Centre National de la Recherche Scientifique, University of North Carolina at Chapel Hill, Genomics (United Kingdom), Washington University in St. Louis, University of Lisbon, University of Iowa, Howard Hughes Medical Institute, Battelle, The Ohio State University, Nationwide Children's Hospital, Ospedale Santa Maria, Yale University, University of Alberta, Center for Human Genetics, Vanderbilt University Medical Center, University of Pennsylvania
Protocol cited in 107 other protocols
Variable analysis
- Autism Diagnostic Interview-Revised (ADI-R)
- Autism Diagnostic Observation Schedule (ADOS)
- DNA source (blood, buccal-swabs, or cell-lines)
- CNVs (Copy Number Variations)
- Individuals with known karyotypic abnormalities or genetic disorders were excluded
- 1,287 EA controls passing all QC-filters included 1,261 individuals recruited as controls for the study of addiction (SAGE) and 26 HapMap samples
- An additional 3,677 EA controls from three separate studies genotyped on other platforms were also used
- Potential systematic measurement differences between cases and controls were controlled for in the primary analyses
- None specified
- None specified
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