Standardized PAM50 Gene Expression Analysis

The levels of expression of the genes of prediction analysis of microarray 50
(PAM50) were normalized and standardized relative to five housekeepers, as
described.^{27 (link)} The samples were classified using the published
PAM50 algorithm into breast cancer subtypes: luminal A, luminal B,
basal-like, HER2-enriched, normal-like, and not applicable (NA).

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Shin J., Ham B., Seo J.H., Lee S.B., Park I.A., Gong G., Kim S.B, & Lee H.J. (2023). Immune repertoire and responses to neoadjuvant TCHP therapy in HER2-positive breast cancer. Therapeutic Advances in Medical Oncology, 15, 17588359231157654.

Publication 2023

Basal Breast cancer Genes expression microarray analysis Her2

Corresponding Organization : Ulsan College

Other organizations : Kangbuk Samsung Hospital

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Variable analysis

independent variables

Levels of expression of the genes of prediction analysis of microarray 50 (PAM50)

dependent variables

Breast cancer subtypes (luminal A, luminal B, basal-like, HER2-enriched, normal-like, and not applicable (NA))

control variables

The levels of expression of the genes of PAM50 were normalized and standardized relative to five housekeepers

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