522 SGBs were selected for inclusion in the tree of Fig. 4 that are: i) detected in 1% or more of the adult stool metagenome samples, (ii) had at least 10 genomes, (iii) have three or more relevant ARG families, or showed significant association with one resistotype (≥5-fold difference in mean relative abundance and p < 0.05 by Mann–Whitney tests after Benjamini–Hochberg adjustment).
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