This exploratory pilot study used a retrospective cross-sectional design to evaluate the practical relevance of YKL-40 (and other blood parameters) to delineate between BA subjects and COPD subjects. To the best of our knowledge, such basic information is lacking in Europe and is scarce around the world [18 (link),19 (link),20 (link)]. Hence, a group of age- and sex- matched patients was selected in order to obtain evidence-based information about the clinical applicability of these biomarkers.
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