fMRI Data Preprocessing Protocol for Neuroimaging Studies

fMRI data (repetition time/echo time = 2000/30 ms, slice thickness = 4 mm, number of slices = 36, matrix size = 64 × 64, field of view = 240 × 240 mm, flip angle = 90°) were acquired during the task using a PHILIPS Achieva 3.0T whole-body scanner(Amsterdam, Netherlands) at Second Xiangya Hospital. The fMRI data were preprocessed using statistical parametric mapping (SPM12, http://www.fil.ion.ucl.ac.uk/spm). First, the images were realigned to the first image obtained in each session using six-parameter rigid body transformation. Second, all images were spatially normalized to a Montreal Neurological Institute template with affine registration, followed by nonlinear transformation, using a voxel size of 2 × 2 × 2 mm. Finally, the data were smoothed with an 8-mm full width at half maximum Gaussian kernel [36 (link)].

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Zhang J., Li B., Gao J., Shi H., Wang X., Jiang Y., Ming Q., Gao Y., Ma R, & Yao S. (2015). Impaired Frontal-Basal Ganglia Connectivity in Male Adolescents with Conduct Disorder. PLoS ONE, 10(12), e0145011.

Publication 2015

Achieva 3.0T whole-body scanner

Body Echo Fmri Rigid

Corresponding Organization : Central South University

Other organizations : Jianghan University, Air Force Medical University, University of Hong Kong, Shanghai Normal University

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Repetition time (TR) = 2000 ms
Echo time (TE) = 30 ms
Slice thickness = 4 mm
Number of slices = 36
Matrix size = 64 × 64
Field of view = 240 × 240 mm
Flip angle = 90°
MRI scanner: PHILIPS Achieva 3.0T whole-body scanner
Preprocessing: Realignment, spatial normalization, and smoothing using SPM12

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