The study was conducted according to the guidelines of the Declaration of Helsinki and approved by the Institutional Review Board of the Mexican Social Security Institute (protocol 2021–1909-106, August 9, 2021). This is a retrospective and non-interventional study, where medical records were consulted and data in the public repository are de-identified.
This study was carried out with records from patients hospitalized in the Zone General Hospital No. 4 “Villa Guadalupe” located in Guadalupe, Nuevo Leon, Mexico. Patients 60 of years old and older with confirmed COVID-19 diagnosis by RT-PCR test and hospitalized between December 1, 2020 and January 5, 2021 were included. A database was collected that included social security number, age, comorbidities, days of hospitalization, outcome, and date of discharge or death. Database, raw and processed are available at Mendeley Data, V1,https://doi.org/10.17632/z4z22nbmmz.1 . ABC-GOALScl, which incorporates clinical and laboratory results, was used and scored as previously described [13 (link)]. This model includes sex, systolic arterial pressure (SAP), presence or absence of dyspnea by respiratory frequency (RF), Charlson comorbidity index, glucose serum levels, obesity, albumin serum levels, lactate dehydrogenase (LDH) serum levels, and SpFi coefficient (Saturation of oxygen/fraction of inspired oxygen, SO2/FiO2, ratio). Subjects who had incomplete clinical records, were diagnosed with Acinetobacter spp. infection or Clostridium difficile, had records that came from another unit, or were directly admitted to the ICU were excluded. Files from subjects who voluntarily requested to leave the study were deleted.
The distribution of continuous variables was evaluated with Kolmogorov–Smirnov. Descriptive statistics were used to analyze the data; qualitative variables are described in frequencies and percentages. For comparison of qualitative variables, chi-squares and stepwise multivariate logistic ordinal regression models were run to calculate adjusted odds ratio (OR) and 95% Confidence Interval (CI) for each component of the ABC-GOALScl score. For quantitative data, a t–test and a Mann–Whitney U test were performed. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and the area under the curve (AUC) were calculated, and a value of p < 0.05 was considered significant.
This study was carried out with records from patients hospitalized in the Zone General Hospital No. 4 “Villa Guadalupe” located in Guadalupe, Nuevo Leon, Mexico. Patients 60 of years old and older with confirmed COVID-19 diagnosis by RT-PCR test and hospitalized between December 1, 2020 and January 5, 2021 were included. A database was collected that included social security number, age, comorbidities, days of hospitalization, outcome, and date of discharge or death. Database, raw and processed are available at Mendeley Data, V1,
The distribution of continuous variables was evaluated with Kolmogorov–Smirnov. Descriptive statistics were used to analyze the data; qualitative variables are described in frequencies and percentages. For comparison of qualitative variables, chi-squares and stepwise multivariate logistic ordinal regression models were run to calculate adjusted odds ratio (OR) and 95% Confidence Interval (CI) for each component of the ABC-GOALScl score. For quantitative data, a t–test and a Mann–Whitney U test were performed. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and the area under the curve (AUC) were calculated, and a value of p < 0.05 was considered significant.
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