Comprehensive Antibody and Compound Panel

The following antibodies were used: GLS (#ab93434, Abcam, Cambridge, MA, USA), AREG (#sc74501, Santa Cruz Biotechnology, Dallas, USA), MLX (#85570 s, Cell signaling, Danvers, MA, USA), Lamin B1 (#12586 s, Cell signaling), caspase 3 (#9664 s, Cell signaling), GAPDH (#CSB-PA00025A0Rb, Cusabio biotech, Wuhan, China), Bcl-2 (#CSB-PA000983, Cusabio biotech) and β-actin (#ABT264, Sigma, St. Louis, MO, USA). AOA, EGCG, DMKG, NAC, glutathione, DOX, cisplatin, camptothecin, ETS, and 5-fluorouracil were purchased from Sigma. BPTES was purchased from Cayman Chemical (Ann Arbor, MI, USA). CB-839 was obtained from Selleckchem (Houston, TX, USA). shRNAs for AREG (SHCLNDTRCN0000117992 and SHCLNDTRCN0000117996) were purchased from Sigma. shRNAs for GLS were described previously [10 (link)].