Comprehensive Metabolic Biomarker Analysis

Laboratory measurements were performed at Zhongnan Hospital for the current study. Kidney function parameters (creatinine, urea nitrogen, uric acid and eGFR[19 (link)]) and serum glucose were examined by the AU5800 Chemistry Analyzer (Beckman). The HA-8160 Glycohemoglobin Analyzer (ADAMS) was used to measure blood glycated hemoglobin (HbA1c). Serum insulin was assayed by the i4000SR Immunology Analyzer (Abbott Laboratories).

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Yang Y., Zeng C., Yang K., Xu S., Zhang Z., Cai Q., He C., Zhang W, & Liu S.M. (2022). Genome-wide Analysis Reflects Novel 5-Hydroxymethylcytosines Implicated in Diabetic Nephropathy and the Biomarker Potential. Extracellular vesicles and circulating nucleic acids, 3(1), 49-60.

Publication 2022

AU5800 Chemistry Analyzer i4000SR Immunology Analyzer

Blood Creatinine Egfr Glucose Glycated hemoglobin Insulin Kidney Nitrogen Serum Urea Uric acid

Corresponding Organization :

Other organizations : Zhongnan Hospital of Wuhan University, Wuhan University, Northwestern University, Howard Hughes Medical Institute, University of Chicago

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Variable analysis

independent variables

Not explicitly mentioned

dependent variables

Kidney function parameters (creatinine, urea nitrogen, uric acid and eGFR)
Serum glucose
Blood glycated hemoglobin (HbA1c)
Serum insulin

control variables

Not explicitly mentioned

controls

No positive or negative controls were explicitly mentioned in the provided information.

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