Patients registered in the Korean COPD Subtype Study (KOCOSS) were recruited from 48 tertiary referral hospitals in Korea and were required to visit the hospital to update their COPD status by self-administered questionnaires at least every 6 months.27 (link) The inclusion criteria were as follows: age ≥40 years and post-bronchodilator forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) <0.7. The medical history taken from patient questionnaires as well as measurements from their initial visit were used as baseline data. Age, sex, St George’s Respiratory Questionnaire (SGRQ-C) response, and the modified Medical Research Council (mMRC) dyspnea scale score of patients were recorded. Post-bronchodilator FEV1, FVC, and FEV1/FVC were checked by pulmonary function tests. Six-minute walk tests (6MWT) were also performed at the time of enrollment.
Protocol detail
KOCOSS Cohort Study of COPD Patients
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Bronchodilator
Copd
Dyspnea
Forced expiratory volume
Forced vital capacity
Korean
Patients
Pulmonary function tests
Respiratory
Six minute walk tests
Vital capacity
Corresponding Organization :
Other organizations : Catholic University of Korea, Inje University Haeundae Paik Hospital, Pulmonary Associates, Incheon St. Mary's Hospital, Incheon Catholic University, Hallym University Sacred Heart Hospital, Hanyang University Guri Hospital, Konkuk University, Seoul St. Mary's Hospital
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Variable analysis
dependent variables
- St George's Respiratory Questionnaire (SGRQ-C) response
- Modified Medical Research Council (mMRC) dyspnea scale score
- Post-bronchodilator forced expiratory volume in 1 second (FEV1)
- Forced vital capacity (FVC)
- FEV1/FVC
- Six-minute walk test (6MWT)
- Post-bronchodilator forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) < 0.7
- Age ≥ 40 years
- Positive control: Not explicitly mentioned.
- Negative control: Not explicitly mentioned.
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