Example 7

    • Initial full mouth one-stage disinfection by rinsing for 2 minutes with a 0.12% chlorhexidine solution.
    • 6 months oral administration of 10 mg of bioavailable silicic acid in the form of choline-stabilized orthosilicic acid (ch-OSA®), wherein silicic acid is stabilized with choline chloride, suitably in the form of two dosage units each containing 5 mg bioavailable silicic acid;
    • Daily administration of two probiotic lozenges, each containing 2 viable strains of Lactobacillus reuteri (1 108 CFU), for instance DSM17938 and ATCC PTA5289, during 6 months.

It is herein preferable, that the administration of the bioavailable silicic acid and the administration of the probiotic lozenges start simultaneously. Alternatively, the administration of the bioavailable silicic acid may precede the administration of the probiotic lozenges during a preparatory period of for instance 3 days up to 14 days, for instance 1 week.

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