Multimodal MRI Acquisition Across Scanners

We analysed T1- and T2-weighted Fluid Attenuated Inversion Recovery (FLAIR) scans acquired across 7 MRI scanners. KLOSCAD and H70-study used Philips 3T Achieva scanners (Philips Medical Systems, The Netherlands) (19 (link), 23 (link)), and PATH used a Philips 1.5T Gyroscan scanner (22 (link)). Of the 474 MAS participants, 240 were scanned with a Philips 3T Intera Quasar scanner, and the remaining 234 with a Philips 3T Achieva Quasar Dual scanner (21 (link)). SLAS-I and SLAS-II used a Siemens 3T Tim Trio and a GE Healthcare 1.5T HDXT scanner, respectively. Detailed imaging acquisition parameters are summarised in Supplementary Table 1.

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Lin K., Wen W., Lipnicki D.M., Mewton L., Chen R., Du J., Wang D., Skoog I., Sterner T.R., Najar J., Kim K.W., Han J.W., Kim J.S., Ng T.P., Ho R., Chua D.Q., Anstey K.J., Cherbuin N., Mortby M.E., Brodaty H., Kochan N., Sachdev P.S, & Jiang J. (2023). Risk factors and cognitive correlates of white matter hyperintensities in ethnically diverse populations without dementia: the COSMIC consortium. medRxiv.

Publication Preprint 2023

Philips 3T Achieva scanners 1.5T Gyroscan scanner 3T Intera Quasar scanner 3T Achieva Quasar Dual scanner 3T Tim Trio 1.5T HDXT scanner

Inversion Slas Trio

Corresponding Organization : UNSW Sydney

Other organizations : Commonwealth Scientific and Industrial Research Organisation, University of Gothenburg, University of Amsterdam, Amsterdam University Medical Centers, Seoul National University, Seoul National University Bundang Hospital, Khoo Teck Puat Hospital, Geriatric Education and Research Institute, National University of Singapore, Neuroscience Research Australia, Australian National University, Prince of Wales Hospital

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Variable analysis

independent variables

MRI scanner type (Philips 3T Achieva, Philips 1.5T Gyroscan, Philips 3T Intera Quasar, Philips 3T Achieva Quasar Dual, Siemens 3T Tim Trio, GE Healthcare 1.5T HDXT)

dependent variables

T1-weighted FLAIR scans
T2-weighted FLAIR scans

control variables

Detailed imaging acquisition parameters (summarized in Supplementary Table 1)

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