Personalized IMRT for SBRT

Targets and OARs were delineated on a MIM Maestro Station (MIM Vista Corp, Cleveland, US-OH) based on four-dimensional CT (4DCT) by radiation oncologists. All structures were reviewed and approved by an experienced radiation oncologist before being used for planning design. All the treatment plans were planned on the average 4DCT image using the Pinnacle Treatment Planning System (TPS) (V9.10, Philips Radiation Oncology Systems, Fitchburg, WI, USA) for an Edge™ linear accelerator (Varian Medical Systems, Palo Alto, CA) equipped with a high-definition 120 multileaf collimator (MLC). The included treatment plans ranged from three to eight fractions, and the planning method was similar to our previous research (15 (link)). In short, treatments were planned following the guidelines of RTOG 0813 (16 (link)) or 0915 (17 (link)) depending on its tumor size, the patient’s physical condition, and location, which employed the IMRT technique with 10 or more 6MV fields. Collimator and couch angles were adjusted according to the individual situation. The collapsed cone convolution (CCC) algorithm was used for dose calculation with a calculation resolution of 1.0 mm.

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Duan Y., Lin Y., Wang H., Kang B., Feng A., Ma K., Chen H., Huang Y., Gu H., Shao Y., Zhou T., Kong Q, & Xu Z. (2021). How Does the Gradient Measure of the Lung SBRT Treatment Plan Depend on the Tumor Volume and Shape?. Frontiers in Oncology, 11, 781302.

Publication 2021

Edge™ linear accelerator

4dct Cone Imrt Linear accelerator Patient Physical Radiation oncologist Tumor

Corresponding Organization : Fudan University

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Variable analysis

independent variables

Planning method (IMRT technique with 10 or more 6MV fields)
Collimator and couch angles (adjusted according to the individual situation)

dependent variables

Delineated targets and OARs on 4DCT scans
Planned treatment plans (ranging from three to eight fractions)

control variables

Delineation of targets and OARs reviewed and approved by an experienced radiation oncologist
Treatment plans planned on the average 4DCT image using the Pinnacle Treatment Planning System (TPS)
Use of an Edge™ linear accelerator (Varian Medical Systems) equipped with a high-definition 120 multileaf collimator (MLC)
Use of the collapsed cone convolution (CCC) algorithm for dose calculation with a calculation resolution of 1.0 mm

controls

Positive control: Guidelines of RTOG 0813 or 0915 for treatment planning based on tumor size, patient's physical condition, and location
Negative control: Not mentioned

Annotations

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