HybridRecon (Version 1.1C, HERMES Medical Solutions AB) was used to perform all reconstructions whilst HybridViewer (Version 2.6F, HERMES Medical Solutions AB) was used to view and analyse the reconstructed images. All images were attenuation corrected using CT data and had the resolution recovery option switched on. Where full MC collimator modelling was not enabled, standard MC scatter correction was carried out.
One acquisition of the phantom was reconstructed with OSEM 1–7 iterations and 15 subsets in order to ascertain the optimum OSEM reconstruction. Previous work on optimisation of 99mTc reconstruction in SPECT imaging had shown that five iterations and 16 subsets yield the best compromise between resolution and noise [20 (link)] but owing to the number of projections at which data were acquired at this institution, 16 subsets were not a possible option. Instead, the nearest alternative of 15 subsets was used. The optimum number of OSEM iterations for 90Y was found via quantitative analysis as described below.
Once the optimised OSEM reconstruction had been identified, all three of the acquisitions were reconstructed with the GE default OSEM protocol (2 iterations and 10 subsets) and the optimised OSEM protocol, both with and without full MC collimator modelling.
One acquisition of the phantom was reconstructed with OSEM 1–7 iterations and 15 subsets in order to ascertain the optimum OSEM reconstruction. Previous work on optimisation of 99mTc reconstruction in SPECT imaging had shown that five iterations and 16 subsets yield the best compromise between resolution and noise [20 (link)] but owing to the number of projections at which data were acquired at this institution, 16 subsets were not a possible option. Instead, the nearest alternative of 15 subsets was used. The optimum number of OSEM iterations for 90Y was found via quantitative analysis as described below.
Once the optimised OSEM reconstruction had been identified, all three of the acquisitions were reconstructed with the GE default OSEM protocol (2 iterations and 10 subsets) and the optimised OSEM protocol, both with and without full MC collimator modelling.
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