Hypertension was defined by systolic blood pressure (SBP) ≥130 mm Hg or diastolic BP (DBP) ≥85 mm Hg. Hyperglycemia was defined by fasting glucose ≥100 mg/dL, and hypertriglyceridemia was defined by fasting triglyceride level ≥150 mg/dL. Decreased HDL-C was defined as an HDL-C level of <40 mg/dL for all boys and girls of <16 years of age and of <50 mg/dL in girls of ≥16 years of age.14 (link) The presence of two or more CMRFs among hypertension, hyperglycemia, hypertriglyceridemia, and decreased HDL-C was classified as multiple CMRFs.
Metabolic syndrome was defined by the International Diabetes Federation (IDF) criteria for children and adolescents.14 (link) A WC of at least the 90th percentile using Korean waist reference data15 was a mandatory criterion for metabolic syndrome. For those of at least 16 years, a WC of ≥90 cm in boys or of ≥85 cm in girls was used to define central obesity.16 (link) Two or more of the following components were also required: a fasting triglyceride level of 150 mg/dL, a fasting glucose concentration of 100 mg/dL or specific treatment, SBP of 130 mm Hg or DBP of 85 mm Hg, or an HDL-C level of <40 mg/dL for both boys and girls of <16 years or of <50 mg/dL in girls of ≥16 years.