Types of treatment were obtained from the CRN and re-grouped as follows:
Surgical treatment was understood as a surgical procedure made with the intent of treating the disease [53 ]. As such, registered diagnostic procedures (exploratory and biopsies) were not included. Surgical treatment for the first up to a fourth diagnosis was combined to create the variable for “Surgery”.
Chemotherapy meant any kind of registered chemotherapeutical treatment [54 ]. Chemotherapy for the first up to a fourth diagnosis was combined to create the variable for “Chemotherapy”.
Radiation therapy was understood as all forms of radiation, including the gamma knife and radioactive iodine [55 ]. Radiation treatment for the first up to a fourth diagnosis was combined to create the variable for “Radiotherapy”.
Hormonal therapy meant having received any kind of hormonal therapy, with or without the combination of other therapies/procedures [56 ]. Hormonal therapy for the first up to a fourth diagnosis was combined to create the variable for “Hormone therapy”.
Multimodal treatments were understood as receiving more than one form of the treatments above (regardless of times one has been diagnosed with cancer). This led to the following combinations, “Surgery and chemotherapy”, “Surgery and radiation”, “Surgery and hormonal therapy”, “Chemotherapy and radiation”, “Chemotherapy and hormonal therapy”, “Surgery, chemotherapy and hormonal therapy”, “Chemotherapy, hormonal therapy and radiation” “Surgery, chemotherapy and radiation”, “Surgery, chemotherapy, radiation and hormonal therapy”.
Surgical treatment was understood as a surgical procedure made with the intent of treating the disease [53 ]. As such, registered diagnostic procedures (exploratory and biopsies) were not included. Surgical treatment for the first up to a fourth diagnosis was combined to create the variable for “Surgery”.
Chemotherapy meant any kind of registered chemotherapeutical treatment [54 ]. Chemotherapy for the first up to a fourth diagnosis was combined to create the variable for “Chemotherapy”.
Radiation therapy was understood as all forms of radiation, including the gamma knife and radioactive iodine [55 ]. Radiation treatment for the first up to a fourth diagnosis was combined to create the variable for “Radiotherapy”.
Hormonal therapy meant having received any kind of hormonal therapy, with or without the combination of other therapies/procedures [56 ]. Hormonal therapy for the first up to a fourth diagnosis was combined to create the variable for “Hormone therapy”.
Multimodal treatments were understood as receiving more than one form of the treatments above (regardless of times one has been diagnosed with cancer). This led to the following combinations, “Surgery and chemotherapy”, “Surgery and radiation”, “Surgery and hormonal therapy”, “Chemotherapy and radiation”, “Chemotherapy and hormonal therapy”, “Surgery, chemotherapy and hormonal therapy”, “Chemotherapy, hormonal therapy and radiation” “Surgery, chemotherapy and radiation”, “Surgery, chemotherapy, radiation and hormonal therapy”.
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