A 75-year-old woman was admitted on 13 May 2021 to a University Hospital in Rio de Janeiro, Brazil, due to an arterial ulcer in the left foot (Fontaine IV Peripheral Arterial Disease). The disease started a year before and clinical treatments were unsuccessful, leading to bone exposure. Therefore, she was being prepared for a surgical amputation. Positive polymerase chain reaction results from two nasal swabs for SARS-CoV-2 was found twice, 30 and 10 days before admission, and she was treated symptomatically at home. Remarkable data in her past pathological history are systemic arterial hypertension, stroke with resulting aphasia and past history of smoking. She was started on intravenous antimicrobials (piperacillin and tazobactam) and heart monitoring due to the atrial fibrillation. Her general condition worsened quickly, showing drowsiness with disorientation, bradycardia and hypotension, metabolic acidosis, leukocytosis and elevated C-reactive protein. At that time, a nasal swab antigen test did not detect SARS-CoV-2. Two blood samples were collected and sent to the laboratory for culture approximately 6 hours before she died due to the septic shock, 4 days after hospitalization, on 17 May 2021. Yeast-like organisms were isolated from both blood culture samples (Figure 1 A).
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